Ofloxacin is used for which ocular condition?

• A. Post-operative corneal ulcers
• B. Bacterial conjunctivitis
• C. Allergic conjunctivitis
• D. Dry eye

Answer: (A)

Ofloxacin is a topical fluoroquinolone antibiotic used for ocular infections because it reliably penetrates the cornea and kills a broad range of bacteria by inhibiting bacterial DNA gyrase and topoisomerase IV. This makes it particularly effective for corneal infections, such as corneal ulcers, including those that can occur after eye surgery when the cornea is at risk for infection. Among the options, post-operative corneal ulcers represent a bacterial keratitis scenario where a potent, cornea-penetrating antibiotic is especially appropriate, which is why this indication is the best fit. Bacterial conjunctivitis can also be treated with an antibiotic, but the emphasis for ofloxacin here is its role in treating deeper, corneal infections. Allergic conjunctivitis and dry eye are non-infectious conditions that do not require antibiotics.